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Different applications, quantity of throughput and final end products often designate the method employed to grind materials. Crushers are commonly shearing or compression disruptors and are used to create larger particles in the 50-100 mm range. These particles are often just a primary step in some processing schemes. Most crushers are able to either process a large continuous stream of materials or larger batches. Grinders often produce smaller particles in smaller scales. There are many types of grinders based on ...

The most common method for obtaining a homogeneous sample is grinding of comminution. Grinding samples has many benefits for sample preparation since it increases homogeneity, increases surface area and decreases particle size which can improve extraction efficiency. Some of the negatives regarding grinding samples are: potential contamination, increase in moisture, evaporation, loss or alteration of volatile compounds or labile constituents, and safety issues regarding grinding.

Sample preparation is the process where a representative piece of material, chemical or substance is extracted from a larger amount, bulk or batch for subsequent analysis. Representative samples are selected to accurately reflect the larger group and represent the characteristics of the whole material. Ideally representative samples are homogeneous or similar in nature, but when that is not possible, the best attempts must be made to achieve samples which represent the majority of the characteristics of the larger grouping.

SPEX SamplePrep’s Freezer/Mill is a cryogenic grinder specifically designed for milling and grinding of tough or temperature sensitive samples. In a recent study, the Freezer/Mill was used in Microplastic research.

The SPEX SamplePrep Geno/Grinder, an automated high-throughput plant & animal tissue homogenizer and cell lyser, played a key part in vaccine research.