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A Modified QuEChERS Method for the Determination of Organochlorine Pesticides in Serum

Application Notes UCT-SP05:

Organochlorine (OC) pesticides are hydrocarbons with multiple chlorine substitutions. They are primarily used as insecticides. OC pesticides do not break down easily as the chlorine-carbon bonds are very strong. As such they remain in the environment long after application and bio-accumulate in organisms long after exposure. They are toxic and some are known or suspected human carcinogens, such as 4,4'-DDT, 4,4'-DDD, and the lindanes. Many OC pesticides are banned or have restricted use. These chemicals are frequently found in human body tissue, blood, fat and breast milk. This application employs a modified QuEChERS extraction and a fast, push-through cartridge clean-up for the determination of OC pesticides in human serum.

This application note was authored by UCT. Please complete the information in the "Download Application Note" box to download the complete article.