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Analysis of Neonicotinoids in Honey by QuEChERS and UHPLC-MS/MS

Application Notes UCT-SP04:

Neonicotinoids are a relatively new class of insecticide that were introduced as an alternative to organophosphate, carbamate and pyrethroid insecticides. Their novel mode of action works by irreversibly binding to nicotinic acetylcholine receptors, resulting in paralysis and death of insects. Since their introduction in the 1990s the neonicotinoids have been used extensively in crop protection. However, they have recently come to under increasing scrutiny over their environmental and ecological impact, especially their role in bee deaths and colony collapse disorder (CCD)[1]. It has been reported that neonictinoid residues can accumulate in the pollen and nectar of treated plants and poses a potential risk to honey bees[2]. In addition, neonicotinoid residues can be transferred to products derived from bees, including the popular food source honey[3]. Due to potential negative impact, the European Union recently restricted the use of three neonicotinoids (clothianidin, thiamethoxam, and imidacloprid) for a period 2 years[4]. 

This application was authored by UCT. Please complete the information in the "Download Application Note" box to download the complete article.